The Ultimate Evil (Literal or metaphorical Embodiments of Evil)

1: DIO Brando (JoJo’s Bizarre Adventure) - Referred to by Araki multiple times to be the Ultimate Evil of the JoJo universe

2: Janemba (Dragon Ball Z: Fusion Reborn) - The physical manifestation of evil possessing a young boy

3: Junko Enoshima (Danganronpa) - The Ultimate Despair in the world of Danganronpa, wanting to spread as much of it possible

3: Judge Holden (Bloody Meridian) - Represents the evil of the Wild West. I almost forgot him but remembered that if I don’t put him, some hilarious person is gonna put “Bat Themed Heroes!!”

And no, AM or Qu don’t count before anyone puts them