Lines that broke me

On my umpteenth rewatch of all the seasons and I somehow forgot this line from Jawbone, "you're real easy to love and anyone who couldn't figure that out is a real bozo."

Instant tears and a deep love for a fictional werewolf that will tell stories about blowing someone in a truckstop bathroom at a drop of a hat. What lines from a PC or NPC will destroy you emotionally no matter how many times you hear it?

A close second, also from Jawbone, "you have a god damn medical condition and that's nothing to be ashamed of."

Edit for spelling